COMMITTEE MEMBERSHIP
Member of WHO/IUIS Allergen Nomenclature Sub-Committee (2019-present)
Member of Immunotherapy and Molecular Allergology and Allergens Committees of Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI) (2019-present)
EDITOR
Co-Chief Editor of Asian Pacific Journal of Allergy and Immunology since 2015
Associate Editor of Asian Biomedicine Journal since 2010
Associate Editor of Frontiers in Allergy (Section: Allergens) since 2020
EXPERTISE
Protein biochemistry, molecular allergology, recombinant vaccine development (DNA, mRNA, subunit, virus-like particles).
Main research topic: house dust mite (HDM) allergy.
Molecular diagnosis of HDM allergy.
Development of new molecular allergen-specific immunotherapy for the prevention or treatment of HDM allergy
Characterization of innate immune activation by HDM allergens
Publications 2018-2023
1)T. Jarupalee, P. Chatchatee, K. Komolpis, N. Suratannon, S. Roytrakul, Y. Yingchutrakul, W. Yimchuen, P. Butta, A. Jacquet, T. Palaga. Detecting Allergens From Black Tiger Shrimp Penaeus monodon That Can Bind and Cross-link IgE by ELISA, Western Blot, and a Humanized Rat Basophilic Leukemia Reporter Cell Line RS-ATL8. Allergy Asthma Immunol Res. 2018 Jan;10(1):62-76
2) T. Soongrung, K. Mongkorntanyatip, T. Peepim, A. Buaklin, M. Le Mignon, N. Malainual, E. Nony, A. Jacquet. The Blomia tropicalis allergen Blo t 7 stimulates innate immune signaling pathways through TLR2. Clin Exp Allergy. 2018; 48(4):464-474.
3) A. Chevigné, A. Jacquet. Emerging roles of the protease allergen Der p 1 in house dust mite-induced airway inflammation. J Allergy Clin Immunol. 2018;142:398-400.
4) P. Pulsawat, T. Soongrung, P. Satitsuksanoa, M. Le Mignon, S. Khemili, D. Gilis, E. Nony, M.W. Kennedy, A. Jacquet. The house dust mite allergen Der p 5 binds lipid ligands and stimulates airway epithelial cells through a TLR2-dependent pathway. Clin Exp Allergy. 2019; 49:378-390
5)E. Haspeslagh, M. Vanheerswynghels, K. Deswarte, J. van Moorleghem, A. Jacquet, BN. Lambrecht, H. Hammad. Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF. J Allergy Clin Immunol. 2019 Feb 20. pii: S0091-6749(19)30267-2. doi: 10.1016/j.jaci.2019.02.007
6) A. Jacquet. Perspectives in Allergen-Specific Immunotherapy: Molecular Evolution of Peptide- and Protein-Based Strategies. Curr Protein Pept Sci. 2019 Jul 18.
doi: 10.2174/1389203720666190718152534
7) A. Jacquet, C. Robinson. Proteolytic, Lipidergic and Polysaccharide Molecular Recognition Shape Innate Responses to House Dust Mite Allergens. Allergy 2020;75:33-53
8) P. Pechsrichuang, A. Jacquet. Molecular approaches to allergen-specific immunotherapy: Are we so far from clinical implementation? Clin Exp Allergy. 2020 May;50(5):543-557
9) T. Soongrung K. Mongkorntanyatip, T. Peepim, S. Jitthamstaporn, P. Pitakpolrat, T. Kaewamatawong, C.M. Janitzek, S. Thrane, A.F. Sander, A. Jacquet. Virus-like particles displaying major HDM allergen Der p 2 for prophylactic allergen immunotherapy. Allergy. 2020 May;75(5):1232-1236
10) T. Boonpiyathad, P. Pradubpongsa, W. Mitthamsiri, P. Satitsuksanoa, A. Jacquet, A. Sangasapaviliya. Allergen-specific immunotherapy boosts allergen-specific IgD production in HDM-sensitized asthmatic patients. Allergy. 2020 Jun;75(6):1457-1460
11) K. Kowal, A. Pampuch, G. Siergiejko, Z. Siergiejko, E. Swiebocka, CR. Schlachter, M. Chruszcz, A. Jacquet. Sensitization to major Dermatophagoides pteronyssinus allergens in house dust mite allergic patients from North Eastern Poland developing rhinitis or asthma. Adv Med Sci. 2020 May 28;65(2):304-309
12) T. Techawiwattanaboon, C Barnier-Quer, T. Palaga, A. Jacquet, N. Collin, N. Sangjun, P. Komanee, K. Patarakul. A Comparison of Intramuscular and Subcutaneous Administration of LigA Subunit Vaccine Adjuvanted with Neutral Liposomal Formulation Containing Monophosphoryl Lipid A and QS21. Vaccines (Basel). 2020 Sep 1;8(3):E494
13) DL. Wannigama, A. Jacquet. NOD2-dependent BCG-induced trained immunity: a way to regulate innate responses to SARS- CoV2? Int J Infect Dis. 2020 Sep 24:S1201-9712(20)32145-7.
14) T. Boonpiyathad, P. Tantilipikorn, K. Ruxrungtham, P. Pradubpongsa, W. Mitthamsiri, A. Piedvache, P. Thantiworasit, S. Sirivichayakul, A. Jacquet, N. Suratannon, P. Chatchatee, N. Morisaki, H. Saito, A. Sangasapaviriya, K. Matsumoto, H. Morita. IL-10-producing innate lymphoid cells increased in house-dust-mite allergic rhinitis patients following immunotherapy.
J Allergy Clin Immunol. 2020 Oct 30:S0091-6749(20)31554-2.
15) P. Pechsrichuang, S. Namwongnao, A. Jacquet. Bioengineering of Virus-like Particles for the Prevention or Treatment of Allergic Diseases. Allergy Asthma Immunol Res. 2021 Jan;13(1):23-41
16) A. Jacquet. Characterization of Innate Immune Responses to House Dust Mite Allergens: Pitfalls and Limitations. Front.Allergy, 2021 March ;2:662378.
17) DL Wannigama, M Amarasiri, C Hurst, P Phattharapornjaroen, S Abe, P Hongsing, SMAH Rad, L Pearson, T Saethang, S Luk-In, N Kueakulpattana, RJ Storer, P Ounjai, A Jacquet, A Leelahavanichkul, T Chatsuwan . Tracking COVID-19 with wastewater to understand asymptomatic transmission. Int J Infect Dis. 2021 May 11:S1201-9712(21)00406-9
18) A. Jacquet. Nucleic acid vaccines and CpG oligodeoxynucleotides for allergen immunotherapy.
Curr Opin Allergy Clin Immunol. 2021;21(6):569-575.
19) W. Rohhimi, JW. Tan, KY. Liew, A. Jacquet, HH. Harith, DA. Israf, CL.Tham. Zerumbone attenuates house dust mite extract-induced epithelial barrier dysfunction in 16HBE14o- cells.
Immunopharmacol Immunotoxicol. 2021 Dec;43(6):813-824
20) MG. Alameh, I. Tombácz, E. Bettini, K. Lederer, C. Sittplangkoon, JR. Wilmore, BT. Gaudette, OY. Soliman, M. Pine, P. Hicks, TB. Manzoni, JJ. Knox, JL. Johnson, D. Laczkó, H. Muramatsu, B. Davis, W. Meng, AM. Rosenfeld, S. Strohmeier, PJC. Lin, BL. Mui, YK. Tam, K. Karikó, A. Jacquet, F. Krammer, P. Bates, MP. Cancro, D. Weissman, ET. Luning Prak, D. Allman, M. Locci, N. Pardi. Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses, Immunity. 2021, 54(12):2877-2892.
21) S. Jitthamstaporn, AF. Sander and A. Jacquet. Virus-like particles displaying recombinant Der p 1 allergen to optimize IgG blocking antibody response. Allergy. 2022;77(2):664-667.
22) AMS. Fernandes, ES. da Silva, EF. Silveira, EMMA. Belitardo, LF. Santiago, RC. Silva, V. Dos Santos Alves, DM. Carneiro, F. Ferreira, A. Jacquet, LGC. Pacheco, NM. Alcantara-Neves, CS. Pinheiro CS. Recombinant T-cell epitope conjugation: A new approach for Dermatophagoides hypoallergen design. Clin Exp Allergy. 2022 Sep 29. doi: 10.1111/cea.14238
23) K. Kasakura, Y. Kawakami, A. Jacquet, T. Kawakami. Histamine-Releasing Factor Is a Novel Alarmin Induced by House Dust Mite Allergen, Cytokines, and Cell Death. J Immunol. 2022 Nov 15;209(10):1851-1859
24) W. Ramírez, D. Torralba, V. Bourg, M. Lastre, O. Perez, A. Jacquet, A. Labrada. Immunogenicity of a novel anti-allergic vaccine based on house dust mite purified allergens and a combination adjuvant in a murine prophylactic model. Front Allergy. 2022 Nov 17;3:1040076
25) S. Jitthamstaporn, R. Inthong, D. Audomsun, S. Chanasit, C. Thanasarnthungcharoen, PJC Lin, D. Weissman, N. Pardi, A. Jacquet. Nucleoside-modified mRNA vaccines yield robust blocking antibody responses against major house dust mite allergens. Allergy. 2023 Jan;78(1):315-318
26) P. Kiatiwat, A. Sangasapaviliya, P. Pradubpongsa, S. Sangkanjanavanich, C. Chiewchalermsri, A. Jacquet, N. Jaisupa, S. Jindarat, T. Boonpiyathad, W. Mitthamsiri. Switching from subcutaneous to sublingual immunotherapy during the maintenance phase in patients with house dust mite allergy.
Allergy. 2023 Feb 8. doi: 10.1111/all.15669.
27) C. Chiewchalermsri, S. Sangkanjanavanich,P. Pradubpongsa, W. Mitthamsiri, N. Jaisupa, S. Jindarat, S. Buranapraditkun, A. Jacquet, A. Sangasapaviliya, T. Boonpiyathad. Randomized, Double-Blind, Placebo-Controlled Trial of Vitamin D Supplementation in the Build-up Phase of House Dust Mite-Specific Immunotherapy. Allergy Asthma Immunol Res. 2023; 10.4168/aair.2023.15.e7
28) WT. Soh, J. Zhang, MD. Hollenberg, H. Vliagoftis, ME. Rothenberg, CL. Sokol, C. Robinson, A. Jacquet. Protease allergens as initiators-regulators of allergic inflammation. Allergy. 2023 May;78(5):1148-1168.
29) A. Jacquet. The HDM allergen orchestra and its cysteine protease maestro: Stimulators of kaleidoscopic innate immune responses. Mol Immunol. 2023 Mar 6;156:48-60
30) S. Dramburg, C. Hilger, A.F. Santos, L. de las Vecillas, R.C. Aalberse, N. Acevedo, L. Aglas, F. Altmann, K. L. Arruda, R. Asero, B. Ballmer-Weber, D. Barber, K. Beyer, T. Biedermann, M. B. Bilo, S. Blank, P.P. Bosshard, H. Breiteneder, H. A. Brough, M. Bublin, D. Campbell, L. Caraballo, J.C. Caubet, G. Celi, M.D. Chapman, M. Chruszcz, A. Custovic, R. Czolk, J. Davies, N. Douladiris, B. Eberlein, M. Ebisawa, A. Ehlers, P. Eigenmann, G. Gadermaier, M. Giovannini, F. Gomez, R. Grohman, C. Guillet, C. Hafner, R.G. Hamilton, M. Hauser, T. Hawranek, H.J. Hoffmann, T. Holzhauser, T. Iizuka, A. Jacquet, T. Jakob, B. Janssen-Weets, U. Jappe, M. Jutel, T. Kalic, S. Kamath, S. Kespohl, J. Kleine-Tebbe, E. Knol, A. Knulst, J.R. Konradsen, P. Korošec, A. Kuehn, G. Lack, T.-M. Le, A. Lopata, O. Luengo, M. Mäkelä, A. Maria Marra, C. Mills, M. Morisset, A. Muraro, A. Nowak-Wegrzyn, R. Nugraha, M. Ollert, K. Palosuo, E.A. Pastorello, S.U. Patil, T. Platts-Mills, A. Pomés, P. Poncet, E. Potapova, L.K. Poulsen, C. Radauer, S. Radulovic, M. Raulf, P. Rougé, J. Sastre, S. Sato, E. Scala, J.M. Schmid, P. Schmid-Grendelmeier, D. Schrama, H. Sénéchal, C. Traidl-Hoffmann, M. Valverde-Monge, M. van Hage, R. van Ree, K. Verhoeckx, S. Vieths, M. Wickman, J. Zakzuk, P.M. Matricardi, K. Hoffmann-Sommergruber. EAACI Molecular Allergology User’s Guide 2.0. Pediatr Allergy Immunol. 2023; 34: Suppl. S 28, 1-386.
Book chapter
European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User’s guide Edition #2. Platts-Mills, T., Caraballo, L., Jacquet, A., Zakzuk, J. Dust Mite Allergy. 2022; 213-226.